The First study conducted a retrospective comparative analysis of 78 patients with diffuse large B-cell lymphoma who received standard care plus Five-Element Music Therapy and mindfulness meditation. Those who received the combined practice/therapy showed reduced fatigue, anxiety, and depression, as well as better sleep, greater engagement with treatment, and improved overall quality of life, with evidence suggesting multiple interconnected pathways in which intervention at one dimension creates beneficial changes that cascade across multiple physiological domains.
The second study conducted a hospital-based comparative analysis involving 460 patients with lung cancer who received Five-Element Music therapy alongside conventional nursing care, compared to conventional nursing care alone. They showed a significantly greater reduction in cancer-related fatigue, anxiety/depression levels, and improved behavioral, physical, emotional, and cognitive status. Logistic regression indicates that improvements in mood may be associated with increased treatment adherence, supporting this therapy as an effective adjunct for managing symptoms and psychosocial well-being.
The Third study employed a retrospective comparative analysis of patients undergoing surgery and receiving Five-Element Music Therapy alongside routine traditional nursing care. For preoperative patients, they found that, compared to routine care alone, the patients receiving Five-Element Music Therapy showed significant improvements in quality of sleep and a reduction in pain and anxiety. However, subsequent findings indicate short-term stabilization, suggesting that the effects were not sustained beyond the immediate perioperative period.The fourth study was a retrospective study of 156 hospitalized patients with a diagnosis of decompensated liver cirrhosis. They compared the effects of those receiving Five Element Music Therapy in combination with Traditional Chinese Medicine rehabilitation care against those receiving rehabilitation alone. The findings indicate improvements in anxiety, depression levels, and sleep quality, and various nutritional indicators, while no significant between-group differences were observed in liver function outcomes.

